Do I Need a Special Diet During Immunotherapy?

Dr. Sudha Sinha·Medical Oncologist & Hematologist·5 min read
Dr. Sudha Sinha · Senior Consultant & Clinical Director, Medical Oncology, Yashoda Hospitals Somajiguda. Last reviewed: July 2026.
Key Takeaways
  • There's no special diet required during immunotherapy — most people can continue eating a normal, balanced diet.
  • What matters more is eating enough to maintain your strength, and staying well hydrated.
  • Gut symptoms — nausea, diarrhoea, appetite loss — are less common with immunotherapy than with chemotherapy. Don't assume they're routine.
  • Early research suggests a high-fibre, plant-forward diet may support treatment response, but the evidence is still too limited to recommend a specific "immunotherapy diet."
  • Avoid over-the-counter probiotic supplement capsules unless your oncologist has specifically prescribed one.

What Should I Eat During Immunotherapy?

There's no special immunotherapy diet backed by evidence. The same principles that apply to eating well during any cancer treatment apply here too: adequate protein, adequate calories, food safety, staying hydrated.

Can Diet Improve How Immunotherapy Works? (Research Update)

  • Early research suggests that a high-fibre, plant-forward diet may support a healthier gut microbiome and could improve responses to immunotherapy.
  • So far, this evidence comes mainly from studies in melanoma patients and is still too early to recommend a specific "immunotherapy diet."
  • For now, there is no proven diet that makes immunotherapy work better.
  • If you enjoy eating this way, including more vegetables, fruits, whole grains, and legumes as part of a balanced diet is a sensible choice.

A Caution on Probiotic Supplements

  • 💊Research on gut bacteria and immunotherapy has found that patients taking over-the-counter probiotic supplements had a weaker response than those who didn't.
  • 💊Unless your oncologist has specifically prescribed one, avoid probiotic supplement capsules during treatment.
️ Supplements vs. Food — Not the Same Thing

This caution is about supplement capsules, not food. Curd, buttermilk, and other fermented foods are a different matter and remain a good protein source.

Frequently Asked Questions

These come up repeatedly in clinic. Answers here intentionally repeat the article above, so each stands on its own.

Related Reads

References

General clinical resources used to support patient education on this site. Your personal treatment plan should always be discussed with your oncologist.

  1. National Cancer Institute — Cancer Treatment Overview
  2. ASCO — Cancer.Net Patient Information
  3. PubMed — National Library of Medicine
  4. Indian Journal of Cancer

Questions about your treatment plan?

Our patient coordinator is available on WhatsApp.

WhatsApp 7207815222
WhatsApp